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The average surface temperature varied more widely and was even hotter than previously thought during much of the past 500 million years, according to the most rigorous study so far

Three scientists are honored for developing a class of blockbuster weight-loss drugs. Is a Nobel prize on the way?

A long-awaited calculation of the W boson’s mass agrees with theory, contradicting a previous anomaly that had raised the possibility of new physics beyond the Standard Model

Genetic testing on samples collected during the earliest days of the covid-19 outbreak suggests it is likely that the virus spread from animals to humans at the Huanan seafood market

A meta-analysis of 137 clinical trials finds triptan drugs are among the most effective for treating migraines, while newer ditan and gepant drugs were rated less highly

In the U.S. in the early 1960s the distributor of a thalidomide drug was impatient to get it on the market. But FDA medical examiner Frances Oldham Kelsey wanted more information to prove its safety

African giant pouched rats proved adept at detecting four commonly trafficked products derived from endangered species including rhino horn and elephant ivory

Some researchers dream of solving all mysteries with a common method—but a mathematical paradox may keep such solutions out of reach

Math’s “best-choice problem” could help humans become better decision-makers, at everything from choosing the best job candidate to finding a romantic partner

In online forums the term “cuck” has become synonymous with “sucker” and “loser.” But this use distorts its history and meaning, creating a baseless moral panic that harms both women and science

We are finally untangling the ancient history of the cactus family, revealing some surprising forces that shaped these plants – ­­­­­­and prompting concern for their future

Exoplanets in binary star systems usually orbit both stars, but astronomers have now spotted three planets orbiting one or the other star in a pair

Genetic analysis of a bird flu virus detected in a person in Missouri who didn’t previously have contact with animals offers more details on the case, but experts say there isn’t substantial evidence to suggest human-to-human transmission is happening

Particles of light can spend "negative time" passing through a cloud of extremely cold atoms – without breaking the laws of physics

As the space industry evolves, we need a new set of international regulations to decide who is responsible for safety, the number of satellites in space, and more

A new design for a nuclear battery that generates electricity from the radioactive decay of americium is unprecedentedly efficient

Spanning 23 million light years, or 220 Milky Way galaxies, a set of giant, newly discovered black hole jets known as Porphyrion may change our understanding of black holes and the structure of the universe

Experiments in a state-of-the-art wave tank suggest we have underestimated the potential size and power of rogue waves and the risk they pose to offshore infrastructure

An artificial intelligence model that can identify the calls of eight whale species is helping researchers track the elusive whale behind a perplexing sound in the Pacific

The second-closest planet to the sun is more geologically active than we thought and could have more than 17,000 venusquakes a year